Introduction: Sodium carbonate raise the pH of the snuff to 8–9 in order to facilitate nicotine absorption through the oral mucous membranes. Objective: The objectivity of the present study is to assess the difference between various forms of sodium carbonate in snuff on mucosal conditions
Materials And Methods: The present crosssectional was conducted on 284 participants. Snuff users adding sodiumcarbonate were further splitted into two groups i.e one group using sodiumcarbonate in premixed form ie (already mixed within pouches) and other group adding sodiumcarbonate seperately (freshly mixed). The parametric One way (ANOVA) of variance, Stepwise Regression Analysis and Multiple Logistic Regression Analysis has been done to narrate the relationship between variables of different forms of sodium carbonate in snuff and different oral conditions
Results: The results of the present study reveals highly significant relationship between snuff users using sodium carbonate in freshly mixed (0.001**) form than that of premixed form(p=0.030*).
Conclusion: The present study is dipicting that there seems to be association between the use of sodium carbonate in snuff and oral mucosal lesions.

Key words – smokeless tobacco, snuff, sodiumcarbonate, Oral mucosal lesions.

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